487929 Sigma-AldrichInSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem
Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture.
More>> Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: Methyl-(5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamate, Methyl-5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-ylcarbamate, R17934
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 31430-18-9 | C₁₄H₁₁N₃O₃S |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
|---|---|---|---|
| 487929-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
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| Overview | Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture. Promotes tubulin depolymerization. Also acts as a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK (Kd < 2 µM). The solid form of this compound (Cat. No. 487928) is also available. |
| Catalogue Number | 487929 |
| Brand Family | Calbiochem® |
| Synonyms | Methyl-(5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamate, Methyl-5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-ylcarbamate, R17934 |
| Product Information | |
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| CAS number | 31430-18-9 |
| Form | Liquid |
| Formulation | A 50 mM (10 mg/664 µL) solution of Nocodazole (Cat. No. 487928) in DMSO. |
| Hill Formula | C₁₄H₁₁N₃O₃S |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Microtubules |
| Secondary target | Certain kinases |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 487929-10MGCN | 04055977200393 |
Documentation
InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem MSDS
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InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem 分析证书
| 标题 | 批号 |
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| 487929 |
参考
| 参考信息概述 |
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| Park, H., et al. 2012. Chem. Med. Chem. 7, 53. Bunz, F., et al. 1998. Science 282, 1497. Fleischman, L.F., et al. 1993. Oncogene 8, 771. Pomies, P., and Block, M.R. 1992. Biochem. Biophys. Res. Commun. 189, 1429. Rennison, M.E., et al. 1992. J. Cell Sci. 102, 239. Thyberg, J., and Moskalewski, S. 1992. J. Cell Sci. 103, 1167. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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