420097 Sigma-AldrichInSolution™ JAK Inhibitor I - CAS 457081-03-7 - Calbiochem
InSolution™ JAK Inhibitor I, CAS 457081-03-7, is a 10 mM solution in DMSO. A highly potent, ATP-competitive inhibitor of JAK. (IC50 = 15, 1, 5 & 1 nM for JAK1, 2, 3 & Tyk2, respectively).
More>> InSolution™ JAK Inhibitor I, CAS 457081-03-7, is a 10 mM solution in DMSO. A highly potent, ATP-competitive inhibitor of JAK. (IC50 = 15, 1, 5 & 1 nM for JAK1, 2, 3 & Tyk2, respectively). Less<<同义词: 2-(1,1-Dimethylethyl)-9-fluoro-3,6-dihydro-7H-benz[h]-imidaz[4,5-f]isoquinolin-7-one, P6, Pyridone 6, DBI, JAK1 Inhibitor I, JAK2 Inhibitor I, JAK3 Inhibitor X
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概述
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重要规格表
CAS # | Empirical Formula |
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457081-03-7 | C₁₈H₁₆FN₃O |
Products
产品目录编号 | 包装 | 数量 / 包装 | |
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420097-500UGCN | 塑胶安瓿;塑胶针药瓶 | 500 μg |
References | |
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References | Thompson, J.E., et al. 2002. Bioorg. Med. Chem. Lett. 12, 1219. |
Product Information | |
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CAS number | 457081-03-7 |
ATP Competitive | Y |
Form | Liquid |
Formulation | A 10 mM (500 µg/162 µl) solution of JAK Inhibitor I (Cat. No. 420099) in DMSO. |
Hill Formula | C₁₈H₁₆FN₃O |
Chemical formula | C₁₈H₁₆FN₃O |
Hygroscopic | Hygroscopic |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Physicochemical Information | |
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Cell permeable | Y |
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Materials Information |
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Packaged under inert gas | Packaged under inert gas |
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Specifications |
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Global Trade Item Number | |
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产品目录编号 | GTIN |
420097-500UGCN | 04055977187861 |
Documentation
InSolution™ JAK Inhibitor I - CAS 457081-03-7 - Calbiochem MSDS
职位 |
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InSolution™ JAK Inhibitor I - CAS 457081-03-7 - Calbiochem 分析证书
标题 | 批号 |
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420097 |
参考
参考信息概述 |
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Thompson, J.E., et al. 2002. Bioorg. Med. Chem. Lett. 12, 1219. |
技术信息
标题 |
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JAK/STAT Signaling Research Focus |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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