171264 Sigma-AldrichInSolution™ AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem
The InSolution™ AMPK Inhibitor, Compound C•2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The InSolution™ AMPK Inhibitor, Compound C•2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 6-(4-(2-Piperidin-1-yl-ethoxy)-phenyl)-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, 2HCl, H₂O, Compound C, 2HCl, H₂O, AMPK Inhibitor I
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 866405-64-3 | C₂₄H₂₅N₅O |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
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| 171264-2MGCN | 玻璃瓶 | 2 mg |
| Description | |
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| Overview | A cell-permeable pyrrazolopyrimidine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM in the presence of 5 µM ATP and the absence of AMP). Does not affect the activities of ZAPK, Syk, PKCθ, PKA, or JAK3. Blocks celluar activities induced by AICAr (Cat. No. 123040) or Metformin (Cat. No. 317240). Induces weight loss by attenuating AMPK-mediated food intake in mice. The solid form of this compound (Cat. No. 171260) is also available. |
| Catalogue Number | 171264 |
| Brand Family | Calbiochem® |
| Synonyms | 6-(4-(2-Piperidin-1-yl-ethoxy)-phenyl)-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, 2HCl, H₂O, Compound C, 2HCl, H₂O, AMPK Inhibitor I |
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| CAS number | 866405-64-3 |
| Form | Liquid |
| Formulation | A 10 mM (2 mg/408 µl) solution of AMPK Inhibitor, Compound C, 2HCl, (Cat. No. 171260) in H₂O. |
| Hill Formula | C₂₄H₂₅N₅O |
| Chemical formula | C₂₄H₂₅N₅O |
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| Quality Level | MQ100 |
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| Purity | ≥98% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 171264-2MGCN | 04055977207200 |
Documentation
InSolution™ AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem MSDS
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InSolution™ AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem 分析证书
| 标题 | 批号 |
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| 171264 |
参考
| 参考信息概述 |
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| Yu, P.B., et al. 2008. Nat. Chem. Biol 4, 33. Kim, E.K., et al. 2004. J. Biol. Chem. 279, 19970. Lee, M., et al. 2003. J. Biol. Chem. 278, 39653. Inoki, K., et al. 2003. Cell 115, 577. Fryer, L.G., 2002. FEBS Lett. 531, 189. Zhou, G., et al. 2001. J. Clin. Invest. 108, 1167. |
小册子
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| New Products: Volume 3, 2012 |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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