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A highly potent agonist of NMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts.
Izquierdo, A., et al. 2013. J. Neurosci.33, 4105. Rhodes, V., et al. 2013. J. Neurosci.33, 3380. Yu, X., et al. 2012. Pharmacol. Biochem. & Beh.101, 479. Albasser, M., et al. 2012. Beh. Neurosci.126, 659. Eijkenboom, M., et al. 2000. Neurosci.101, 27. Isacson, O., et al. 1984. Nature.311, 458.
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Regulatory Review
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
-20°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Izquierdo, A., et al. 2013. J. Neurosci.33, 4105. Rhodes, V., et al. 2013. J. Neurosci.33, 3380. Yu, X., et al. 2012. Pharmacol. Biochem. & Beh.101, 479. Albasser, M., et al. 2012. Beh. Neurosci.126, 659. Eijkenboom, M., et al. 2000. Neurosci.101, 27. Isacson, O., et al. 1984. Nature.311, 458.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A highly potent agonist of NMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts.
Form
White solid
CAS number
2552-55-8
Chemical formula
C₅H₆N₂O₄
Structure formula
Purity
≥99% by HPLC
Solubility
H₂O (10 mM)
Storage
Protect from light
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Regulatory Review
References
Izquierdo, A., et al. 2013. J. Neurosci.33, 4105. Rhodes, V., et al. 2013. J. Neurosci.33, 3380. Yu, X., et al. 2012. Pharmacol. Biochem. & Beh.101, 479. Albasser, M., et al. 2012. Beh. Neurosci.126, 659. Eijkenboom, M., et al. 2000. Neurosci.101, 27. Isacson, O., et al. 1984. Nature.311, 458.