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372770 HBDDE - CAS 154675-18-0 - Calbiochem

372770
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
154675-18-0C₁₆H₁₈O₈

Products

产品目录编号包装 数量 / 包装
372770-1MGCN 塑胶安瓿;塑胶针药瓶 1 mg
Description
OverviewA cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKCα (IC50 = 43 µM) and PKCγ (IC50 = 50 µM) over PKCδ, βI, and βII isozymes in in vitro assays. Reported to induce apoptosis in rodent cerebellar granule neurons.
Catalogue Number372770
Brand Family Calbiochem®
Synonyms2,2ʹ,3,3ʹ,4,4ʹ-Hexahydroxy-1,1ʹ-biphenyl-6,6ʹ-dimethanol Dimethyl Ether
References
ReferencesMathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.
Product Information
CAS number154675-18-0
ATP CompetitiveN
FormOrange solid
Hill FormulaC₁₆H₁₈O₈
Chemical formulaC₁₆H₁₈O₈
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKCα
Primary Target IC<sub>50</sub>43 µM against PKCα
Purity≥95% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
372770-1MGCN 04055977212884

Documentation

HBDDE - CAS 154675-18-0 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

HBDDE - CAS 154675-18-0 - Calbiochem 分析证书

标题批号
372770

参考

参考信息概述
Mathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-December-2018 JSW
Synonyms2,2ʹ,3,3ʹ,4,4ʹ-Hexahydroxy-1,1ʹ-biphenyl-6,6ʹ-dimethanol Dimethyl Ether
DescriptionProtein kinase C (PKC) inhibitor. Selectively inhibits PKCα (IC50 = 43 µM) and PKCγ (IC50 = 50 µM) over PKCδ, βI and βII isozymes.
FormOrange solid
CAS number154675-18-0
Chemical formulaC₁₆H₁₈O₈
Structure formulaStructure formula
Purity≥95% by TLC
SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml), or warm H₂O (1 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809.
Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.