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368059 Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem

368059
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概述

Replacement Information

Products

产品目录编号包装 数量 / 包装
368059-1MGCN 塑胶安瓿;塑胶针药瓶 1 mg
368059-5MGCN 塑胶安瓿;塑胶针药瓶 5 mg
Description
OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number368059
Brand Family Calbiochem®
SynonymsZ-IETD-AFC, Caspase-8 Substrate II
References
ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
Product Information
CAS number219138-02-0
ATP CompetitiveN
FormWhite lyophilized solid
Hill FormulaC₃₇H₄₂F₃N₅O₁₃
Chemical formulaC₃₇H₄₂F₃N₅O₁₃
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
368059-1MGCN 07790788049621
368059-5MGCN 04055977192179

Documentation

Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem 分析证书

标题批号
368059

参考

参考信息概述
Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsZ-IETD-AFC, Caspase-8 Substrate II
DescriptionA fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
FormWhite lyophilized solid
CAS number219138-02-0
Chemical formulaC₃₇H₄₂F₃N₅O₁₃
Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
Purity≥97% by HPLC
SolubilityDMSO (1 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.