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341501 FeTMPyP - Calbiochem

Catalyzes the isomerization of peroxynitrite (ONOO⁻) to nitrate (NO3⁻) under physiological conditions and at realistic dose-derived concentrations (kcat = 2.2 x 10⁶M⁻¹s⁻¹).

FeTMPyP - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: 5,10,15,20-Tetrakis(N-methyl-4ʹ-pyridyl)porphinato Iron (III) Chloride, FeIIITMPyP(Cl)

341501
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Empirical Formula
C₄₄H₃₆Cl₅FeN₈

Products

产品目录编号包装 数量 / 包装
341501-10MGCN 塑胶安瓿;塑胶针药瓶 10 mg
Description
OverviewCatalyzes the isomerization of peroxynitrite (ONOO–) to nitrate (NO3–) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O2·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).
Catalogue Number341501
Brand Family Calbiochem®
Synonyms5,10,15,20-Tetrakis(N-methyl-4ʹ-pyridyl)porphinato Iron (III) Chloride, FeIIITMPyP(Cl)
References
ReferencesLee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 46, 703.
Product Information
ATP CompetitiveN
FormBrown solid
Hill FormulaC₄₄H₃₆Cl₅FeN₈
Chemical formulaC₄₄H₃₆Cl₅FeN₈
HS Code2933 59 99
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPeroxynitrite (ONOO-)
Primary Target IC<sub>50</sub>Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
Purity≥90% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
341501-10MGCN 04055977215014

Documentation

FeTMPyP - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

FeTMPyP - Calbiochem 分析证书

标题批号
341501

参考

参考信息概述
Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 46, 703.

小册子

标题
Pathways and Biomarkers of Oxidative Stress
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-June-2008 RFH
Synonyms5,10,15,20-Tetrakis(N-methyl-4ʹ-pyridyl)porphinato Iron (III) Chloride, FeIIITMPyP(Cl)
DescriptionCatalyzes the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also decomposes superoxide radicals (O2•) catalytically. Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH•) radicals. FeTMPyP can also serve as a potential drug for reactive oxygen species (ROS) detoxification.
FormBrown solid
Chemical formulaC₄₄H₃₆Cl₅FeN₈
Structure formulaStructure formula
Purity≥90% by TLC
SolubilityH₂O (50 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity Standard Handling
ReferencesLee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 46, 703.