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341006 Sigma-AldrichEDAC, Hydrochloride

EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

EDAC, Hydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Purity
25952-53-8	≥98% by Titration

Products

产品目录编号	包装	数量 / 包装
341006-25GMCN	玻璃瓶	25 gm	添加到收藏夹添加到收藏夹添加到我的收藏夹
341006-5GMCN	塑胶安瓿;塑胶针药瓶	5 gm	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	Water-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides.
Overview	Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M^-1cm^-1.
Catalogue Number	341006
Brand Family	Calbiochem®
Synonyms	EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl

References
References	Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605. Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415. Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950. Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480. Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090. Yamada, H., et al. 1981. Biochemistry 20, 4836. Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149. Ozawa, H. 1970. Biochemistry 9, 2158. Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

References

Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
Yamada, H., et al. 1981. Biochemistry 20, 4836.
Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
Ozawa, H. 1970. Biochemistry 9, 2158.
Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

Product Information
CAS number	25952-53-8
Form	White solid
Hill Formula	C₈H₁₇N₃ · HCl
Chemical formula	C₈H₁₇N₃ · HCl
Hygroscopic	Hygroscopic
Structure formula Image
Quality Level	MQ200

Applications

Biological Information
Purity	≥98% by Titration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	FF2200000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Protect from Moisture	Protect from moisture
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Unstable in solution. Reconstitute just prior to use.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
341006-25GMCN	07790788054182
341006-5GMCN	04055977215403

Documentation

EDAC, Hydrochloride MSDS

职位
物料安全数据表 (MSDS)

EDAC, Hydrochloride 分析证书

标题	批号
341006	输入批号

参考

参考信息概述
Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605. Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415. Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950. Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480. Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090. Yamada, H., et al. 1981. Biochemistry 20, 4836. Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149. Ozawa, H. 1970. Biochemistry 9, 2158. Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

参考信息概述

小册子

标题
Excitotoxic Glutamate Analogs Technical Bulletin

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-October-2017 JSW
Synonyms	EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
Description	Water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative.
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	25952-53-8
RTECS	FF2200000
Chemical formula	C₈H₁₇N₃ · HCl
Structure formula
Purity	≥98% by Titration
Solubility	H₂O (2-5 mg/ml) or Aqueous buffers (2-5 mg/ml). Avoid amine containing buffers.
Storage	Protect from moisture -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Unstable in solution. Reconstitute just prior to use.
Toxicity	Irritant
References	Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605. Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415. Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950. Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480. Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090. Yamada, H., et al. 1981. Biochemistry 20, 4836. Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149. Ozawa, H. 1970. Biochemistry 9, 2158. Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

种类

Life Science Research > Protein Detection and Quantification > Protein Modification & Labeling Tools

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