324461 Sigma-AldrichE2F Inhibitor, HLM006474 - CAS 353519-63-8 - Calbiochem
The E2F Inhibitor, HLM006474, also referenced under CAS 353519-63-8, controls the biological activity of E2F. This small molecule/inhibitor is primarily used for Cancer applications.
More>> The E2F Inhibitor, HLM006474, also referenced under CAS 353519-63-8, controls the biological activity of E2F. This small molecule/inhibitor is primarily used for Cancer applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 7-((4-Ethoxy-3-methylphenyl)(2-pyridylamino)methyl)-2-methyl-quinolinol
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概述
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Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
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| 324461-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
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| Overview | A cell-permeable 8-hydroxyquinoline compound that is reported to inhibit nuclear E2F complexes DNA binding activity (IC50 = 30 µM) and downregulate E2F expression in the melanoma cell line A375, resulting in eventual apoptosis induction without upregulating p53 expression as commonly seen with traditional chemotherapeutic agents, such as Cisplatin (Cat. No. 232120), doxorubicin (Cat. No. 324380), and VP-16 (Cat. No. 341205). |
| Catalogue Number | 324461 |
| Brand Family | Calbiochem® |
| Synonyms | 7-((4-Ethoxy-3-methylphenyl)(2-pyridylamino)methyl)-2-methyl-quinolinol |
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| References | Ma, Y., et al. 2008. Cancer Res. 68, 6292. |
| Product Information | |
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| CAS number | 353519-63-8 |
| Form | Off-white solid |
| Hill Formula | C₂₅H₂₅N₃O₂ |
| Chemical formula | C₂₅H₂₅N₃O₂ |
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| Quality Level | MQ100 |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| 产品目录编号 | GTIN |
| 324461-10MGCN | 04055977197211 |
Documentation
E2F Inhibitor, HLM006474 - CAS 353519-63-8 - Calbiochem MSDS
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E2F Inhibitor, HLM006474 - CAS 353519-63-8 - Calbiochem 分析证书
| 标题 | 批号 |
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| 324461 |
参考
| 参考信息概述 |
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| Ma, Y., et al. 2008. Cancer Res. 68, 6292. |