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309795 DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem

309795
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
53005-05-3C₁₆H₈N₂O₆S₄ · 2Na

Products

产品目录编号包装 数量 / 包装
309795-250MGCN 塑胶安瓿;塑胶针药瓶 250 mg
Description
OverviewBinds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Catalogue Number309795
Brand Family Calbiochem®
Synonyms4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na
References
ReferencesBettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
Product Information
CAS number53005-05-3
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₆H₈N₂O₆S₄ · 2Na
Chemical formulaC₁₆H₈N₂O₆S₄ · 2Na
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCl- uptake
Primary Target IC<sub>50</sub>150 nM inhibiting Cl- uptake in neuroblastoma cells
Purity≥85% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
309795-250MGCN 04055977216790

Documentation

DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem 分析证书

标题批号
309795

参考

参考信息概述
Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-February-2024 JSW
Synonyms4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na
DescriptionBinds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl- uptake (IC50 = 150 nM) in neuroblastoma cells. Has antiulcerous activity.
FormYellow solid
CAS number53005-05-3
Chemical formulaC₁₆H₈N₂O₆S₄ · 2Na
Structure formulaStructure formula
Purity≥85% by HPLC
SolubilityH₂O (0.5%)
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
ReferencesBettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.