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182015 Cyclo(Arg-Gly-Asp-D-Phe-Val) - CAS 137813-35-5 - Calbiochem

Potent inhibitor of cell adhesion.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: RGDFV Peptide, Cyclic

Primary Target: inhibits tumor cell adhesion to laminin and vitronectin substrates
182015
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
137813-35-5C₂₆H₃₈N₈O₇

Products

产品目录编号包装 数量 / 包装
182015-1MGCN 塑胶安瓿;塑胶针药瓶 1 mg
Description
OverviewPotent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.
Catalogue Number182015
Brand Family Calbiochem®
SynonymsRGDFV Peptide, Cyclic
References
ReferencesShono, T., et al. 2001. Exp. Cell Res. 268, 169.
Matsuno, H., et al. 1994. Circulation 90, 2203.
Noiri, E., et al. 1994. Kidney Int. 46, 1050.
Gurrath, M., et al. 1992. Eur. J. Biochem. 210, 911.
Product Information
CAS number137813-35-5
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluoroacetate salt
Hill FormulaC₂₆H₃₈N₈O₇
Chemical formulaC₂₆H₃₈N₈O₇
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetinhibits tumor cell adhesion to laminin and vitronectin substrates
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
182015-1MGCN 04055977205039

Documentation

Cyclo(Arg-Gly-Asp-D-Phe-Val) - CAS 137813-35-5 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Cyclo(Arg-Gly-Asp-D-Phe-Val) - CAS 137813-35-5 - Calbiochem 分析证书

标题批号
182015

参考

参考信息概述
Shono, T., et al. 2001. Exp. Cell Res. 268, 169.
Matsuno, H., et al. 1994. Circulation 90, 2203.
Noiri, E., et al. 1994. Kidney Int. 46, 1050.
Gurrath, M., et al. 1992. Eur. J. Biochem. 210, 911.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-April-2008 RFH
SynonymsRGDFV Peptide, Cyclic
DescriptionPotent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion.
FormWhite solid
FormulationSupplied as a trifluoroacetate salt
CAS number137813-35-5
Chemical formulaC₂₆H₃₈N₈O₇
Purity≥95% by HPLC
Solubility1 N Acetic acid (5 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesShono, T., et al. 2001. Exp. Cell Res. 268, 169.
Matsuno, H., et al. 1994. Circulation 90, 2203.
Noiri, E., et al. 1994. Kidney Int. 46, 1050.
Gurrath, M., et al. 1992. Eur. J. Biochem. 210, 911.