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219372 Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

219372
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概述

重要规格表

CAS #Empirical Formula
429676-93-7C₃₆H₃₃N₂O₆P

Products

产品目录编号包装 数量 / 包装
219372-1MGCN 塑胶安瓿;塑胶针药瓶 1 mg
219372-5MGCN 玻璃瓶 5 mg
Description
OverviewA potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
Catalogue Number219372
Brand Family Calbiochem®
References
ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
Product Information
CAS number429676-93-7
ATP CompetitiveN
FormWhite solid
Hill FormulaC₃₆H₃₃N₂O₆P
Chemical formulaC₃₆H₃₃N₂O₆P
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationCathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).
Biological Information
Primary Targetcathepsin G
Primary Target IC<sub>50</sub>53 nM
Primary Target K<sub>i</sub>63 nM for cathepsin G
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
产品目录编号 GTIN
219372-1MGCN 04055977202267
219372-5MGCN 04055977202274