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218753 Caspase-5 Inhibitor I

218753
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Empirical Formula
C₃₇H₄₂FN₇O₁₀

Products

产品目录编号包装 数量 / 包装
218753-1MGCN 塑胶安瓿;塑胶针药瓶 1 mg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
Catalogue Number218753
Brand Family Calbiochem®
SynonymsZ-WE(OMe)HD(OMe)-FMK
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Product Information
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₃₇H₄₂FN₇O₁₀
Chemical formulaC₃₇H₄₂FN₇O₁₀
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-1, caspase-4, caspase-5, caspase-8
Puritysingle spot by TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
218753-1MGCN 04055977219098

Documentation

Caspase-5 Inhibitor I MSDS

职位

物料安全数据表 (MSDS) 

Caspase-5 Inhibitor I 分析证书

标题批号
218753

参考

参考信息概述
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-June-2008 JSW
SynonymsZ-WE(OMe)HD(OMe)-FMK
DescriptionA potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₃₇H₄₂FN₇O₁₀
Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Puritysingle spot by TLC
SolubilityDMSO (5 mg/ml)
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Toxicity Standard Handling
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.