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233105 CL-82198 - CAS 1188890-36-9 - Calbiochem

A selective inhibitor of MMP-13 (IC₅₀ = 10 µM).

CL-82198 - CAS 1188890-36-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: MMP-13
233105
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
1188890-36-9C₁₇H₂₂N₂O₃ · HCl

Products

产品目录编号包装 数量 / 包装
233105-5MGCN 塑胶安瓿;塑胶针药瓶 5 mg
Description
OverviewA selective inhibitor of MMP-13 (IC50 = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
Catalogue Number233105
Brand Family Calbiochem®
References
ReferencesChen, J.M., et al. 2000. J. Am. Chem. Soc. 122, 9648.
Product Information
CAS number1188890-36-9
ATP CompetitiveN
FormLight yellow solid
Hill FormulaC₁₇H₂₂N₂O₃ · HCl
Chemical formulaC₁₇H₂₂N₂O₃ · HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-13
Primary Target IC<sub>50</sub>10 µM against MMP-13
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
233105-5MGCN 04055977217629

Documentation

CL-82198 - CAS 1188890-36-9 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

CL-82198 - CAS 1188890-36-9 - Calbiochem 分析证书

标题批号
233105

参考

参考信息概述
Chen, J.M., et al. 2000. J. Am. Chem. Soc. 122, 9648.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-April-2011 RFH
DescriptionA selective inhibitor of MMP-13 (IC50 = 10 µM) that does not appear to act by chelating Zn2+. Binds within the entire S1' pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
FormLight yellow solid
CAS number1188890-36-9
Chemical formulaC₁₇H₂₂N₂O₃ · HCl
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityH₂O (25 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesChen, J.M., et al. 2000. J. Am. Chem. Soc. 122, 9648.