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SCT082 BioTracker Red MAO-A Live Cell Dye

Specific two-photon fluorogenic probe for detecting and visualizing MAO-A activity in live cells, mouse and human tissues.

SCT082
1 mg  
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue NumberSCT082
DescriptionBioTracker Red MAO-A Live Cell Dye
OverviewMonoamine oxidases (MAOs) are important enzymes that catalyze the transformation of various neurotransmitters including serotonin, dopamine, and phenethylamine. They have two functionally distinct but structurally similar isoforms (MAO-A and MAO-B). The ability to differentiate the isoforms by using fluorescence detection/imaging technology is biologically relevant, but challenging with currently available chemical tools (1).

BioTracker Red MAO-A Live Cell Dye is a specific two-photon fluorogenic probe for detecting and visualizing MAO-A activity. This probe may be used to detect MAO-A enzymatic activities in various biological samples, including live mammalian cells, mouse and human tissues by using two-photon fluorescence microscopy with minimal cytotoxicity (1).

Reference:
1. Fang, H., Zhang, H., Li, L., Ni, Y., Shi, R., Li, Z., ... & Huang, W. (2020). Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues. Angewandte Chemie, 132(19), 7606-7611.
Alternate Names
  • Live Cell Imaging Probe
References
Product Information
Detection methodFluorescence
PresentationLyophilized. Yellow solid.
Applications
ApplicationSpecific two-photon fluorogenic probe for detecting and visualizing MAO-A activity in live cells, mouse and human tissues.
Key Applications
  • Cell Based Assays
Application NotesLive cell fluorescent imaging
Biological Information
Molecular Weight266.38
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
SCT082 04061841827955