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SCT041 BioTracker Green Copper Live Cell Dye

Live Cell imaging probe for detection of Copper (Cu+) ion in live cells.

SCT041
5 x 50 nmol  
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue NumberSCT041
DescriptionBioTracker Green Copper Live Cell Dye
OverviewCopper is one of the trace metals required by living organisms and is an essential cofactor for enzyme activities of cytochrome c oxidase, superoxide dismutase, and tyrosinase. On the other hand, abnormal homeostasis of copper leads to severe disorders such as Menkes syndrome and Wilson’s disease, or may be related to Alzheimer’s disease and cancers.

BioTracker Green Copper Live Cell Dye is a fluorescent probe to detect Cu+, which is a dominant redox state of copper in an intracellular reducing environment. The dye is a colorless material with almost no fluorescence. Upon the reaction with Cu+, its fluorescence intensity at 510 nm increases more than 100 times to that before the reaction. However, fluorescence increase is not observed in the presence of reactive oxygen species and other trace metals in cells including Cu2+, Mn2+, Co2+, Ni2+, Fe+, Fe2+ and Zn2+.

Spectral Properties
Absorbance (max): 480nm
Emission (max): 510nm

References
Taki M et al. Development of Highly Sensitive Fluorescent Probes for Detection of Intracellular Copper (I) in Living Systems. J. Am. Chem. Soc. 2010, 132, 17, 5938-5939.
Alternate Names
  • CopperGREENTM
References
Product Information
Detection methodFluorescence
HS Code3204 90 00
PresentationLyophilized
Applications
ApplicationLive Cell imaging probe for detection of Copper (Cu+) ion in live cells.
Key Applications
  • Cell Based Assays
Application NotesLive cell fluorescent imaging. Green fluorescence.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 80% (LC)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker Green Copper Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Packaging Information
Material Size5 x 50 nmol
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
SCT041 04061841588276