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178220 Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem

Antipain, Hydrochloride, CAS 37682-72-7, is a peptidyl arginine aldehyde protease inhibitor of trypsin-like serine proteases, papain, and some cysteine proteases (IC50 = 300 µM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Trypsin-like serine proteases
178220
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
37682-72-7C₂₇H₄₄N₁₀O₆ · HCl

Products

产品目录编号包装 数量 / 包装
178220-10MGCN 塑胶安瓿;塑胶针药瓶 10 mg
178220-5MGCN 玻璃瓶 5 mg
Description
OverviewPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM).
Effective concentration: 1-100 µM.
Catalogue Number178220
Brand Family Calbiochem®
References
ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
Umezawa, H. 1976. Methods Enzymol. 55, 678.
Product Information
CAS number37682-72-7
ATP CompetitiveN
FormWhite or slightly yellowish solid
Hill FormulaC₂₇H₄₄N₁₀O₆ · HCl
Chemical formulaC₂₇H₄₄N₁₀O₆ · HCl
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
ApplicationAntipain, Hydrochloride, CAS 37682-72-7, is a peptidyl arginine aldehyde protease inhibitor of trypsin-like serine proteases, papain, and some cysteine proteases (IC50 = 300 µM).
Biological Information
Primary TargetTrypsin-like serine proteases
Primary Target IC<sub>50</sub>300 µM against trypsin-like serine proteases, papain and some cysteine proteases
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSYV9350800
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
178220-10MGCN 04055977223088
178220-5MGCN 04055977223095

Documentation

Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem 分析证书

标题批号
178220

参考

参考信息概述
Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
Umezawa, H. 1976. Methods Enzymol. 55, 678.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-September-2007 RFH
DescriptionPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain, and some cysteine proteases (IC50 ~500 ng/ml). Effective at concentrations of 1-100 µM.
FormWhite or slightly yellowish solid
CAS number37682-72-7
RTECSYV9350800
Chemical formulaC₂₇H₄₄N₁₀O₆ · HCl
SolubilityH₂O (10 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
Umezawa, H. 1976. Methods Enzymol. 55, 678.