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ABC963 Anti-phospho Mitofusin2 Antibody (Ser442)

Anti-phospho Mitofusin2 Antibody (Ser442) is an antibody against phospho Mitofusin2 (Ser442) for use in Western Blotting, Peptide Inhibition Assay.

Anti-phospho Mitofusin2 Antibody (Ser442) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: MFN2, CPRP1, KIAA0214 UniProt Number: O95140
ABC963
100 µg  
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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, PIARbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC963
DescriptionAnti-phospho Mitofusin2 Antibody (Ser442)
Alternate Names
  • Mitofusin-2
  • Transmembrane GTPase MFN2
Background InformationMitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-phospho Mitofusin2 Antibody (Ser442) is an antibody against phospho Mitofusin2 (Ser442) for use in Western Blotting, Peptide Inhibition Assay.
Key Applications
  • Western Blotting
  • Peptide Inhibition Assay
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human phospho Mitofusin2 (Ser442).
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Rat, Mouse, Bovine, Canine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • MFN2
  • CPRP1
  • KIAA0214
Modifications
  • Phosphorylation
Purification MethodAffinity
UniProt Number
Molecular Weight~86 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected phospho Mitofusin2 (Ser442) in 10 µg of SH-SY5Y cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABC963 04055977137095