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ABN192 Anti-ZFP36L1 Antibody

ABN192
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, R, B, Eq, CaWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN192
DescriptionAnti-ZFP36L1 Antibody
Alternate Names
  • Zinc finger protein 36, C3H1 type-like 1
  • Butyrate response factor 1
  • EGF-response factor 1
  • ERF-1
  • Protein TIS11B
Background InformationAs a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.
References
Product Information
FormatAffinity Purified
Control
  • HeLa cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of ZFP36L1.
Species Reactivity
  • Human
  • Mouse
  • Rat
  • Bovine
  • Horse
  • Canine
Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Horse, and Canine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ZFP36L1
  • BERG36
  • BRF1
  • ERF1
  • RNF162B
  • TIS11B
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~38 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN192 04053252826023