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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABS466 Sigma-AldrichAnti-Trpv4 Antibody, clone 1B2.6

Anti-Trpv4 Antibody, clone 1B2.6 is an antibody against Trpv4 for use in Western Blotting and Immunocytochemistry.

Anti-Trpv4 Antibody, clone 1B2.6 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

分析证书
技术信息

Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: VRL2, VROAC, TRPV4 UniProt Number: Q9HBA0

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, ICC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS466
Description	Anti-Trpv4 Antibody, clone 1B2.6
Alternate Names	Trpv4 Transient receptor potential cation channel subfamily V member 4 TrpV4 Osm-9-like TRP channel 4 OTRPC4 Transient receptor potential protein 12 TRP12 Vanilloid receptor-like channel 2 Vanilloid receptor-like protein 2 VRL-2 Vanilloid receptor-related osmotically-activated channel VR-OAC
Background Information	Transient receptor potential cation channel subfamily V member 4 is a multitransmembrane non-selective cation channel encoded by the TRPV4 (also known as CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VR-OAC, VRL-2, VRL2, VROAC) gene and belong to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the transient receptor potential (TRP)3 superfamily of channels. Ankyrin (ANK) repeats/domains are shown to be important for functional channel expression, and ANK domain mutations are found in patients suffering from Spinal muscular atrophies (SMA, also known as hereditary motor neuropathies) and hereditary motor and sensory neuropathies (HMSN). (PMID 16293632, 20037587, 20037588).

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-Trpv4 Antibody, clone 1B2.6 is an antibody against Trpv4 for use in Western Blotting and Immunocytochemistry.
Key Applications	Western Blotting Immunocytochemistry
Application Notes	Immunocytochemistry Analysis: 10 µg/mL from a representative lot detected Trpv4 in NIH/3T3 cells.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to human Trpv4.
Clone	1B2.6
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Specificity	This antibody is expected to react to all isoforms.
Isotype	IgG2aκ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001170899
Gene Symbol	VRL2 VROAC TRPV4
Purification Method	Protein G Purified
UniProt Number	Q9HBA0
Molecular Weight	~86-98 kDa observed. Uniprot describes 6 isoforms produced by alternative splicing ranging from ~86 to 98 kDa. Uncharacterized band(s) may appear in some lysates.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in SK-MEL-28 cell lysate. Western Blotting Analysis: 0.1 µg/mL of this antibody detected Trpv4 in 10 µg of SK-MEL-28 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS466	04055977145021

Documentation

Anti-Trpv4 Antibody, clone 1B2.6 分析证书

标题	批号
Anti-Trpv4, clone 1B2.6 - 3182595	3182595
Anti-Trpv4, clone 1B2.6 - 3224555	3224555
Anti-Trpv4, clone 1B2.6 - 3462069	3462069
Anti-Trpv4, clone 1B2.6 - 3781059	3781059
Anti-Trpv4, clone 1B2.6 - 3822336	3822336
Anti-Trpv4, clone 1B2.6 - 4095326	4095326
Anti-Trpv4, clone 1B2.6 -2891852	2891852
Anti-Trpv4, clone 1B2.6 -Q2559148	Q2559148
Anti-Trpv4, clone 1B2.6 Monoclonal Antibody	3101501
Anti-Trpv4, clone 1B2.6 Monoclonal Antibody	MABS466

技术信息

标题
White Paper: Further considerations of antibody validation and usage.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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