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ABN356 Anti-Slitrk3 Antibody

ABN356
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN356
DescriptionAnti-Slitrk3 Antibody
Alternate Names
  • SLIT
  • NTRK-like family 3
  • Slitrk3
Background InformationSLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
References
Product Information
FormatAffinity Purified
Control
  • SK-N-SH cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Slitrk3 antibody is validated for use in WB & IHC for the detection of the Slitrk3 protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: Human brain tissue was prepared using heat-induced epitope retrieval (HIER). Immunostaining was performed using 2.5 µg/mL Slitrk3 antibody.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Slitrk3.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~120 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in SK-N-SH cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Slitrk3 in 15 µg of SK-N-SH cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN356 04053252847639