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MABC699 Anti-PAX3, clone 7D8G7 Antibody

MABC699
100 µL  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, ELISAMAscitesMonoclonal Antibody
Description
Catalogue NumberMABC699
DescriptionAnti-PAX3, clone 7D8G7 Antibody
Alternate Names
  • Paired box protein Pax-3
  • HuP2
Background InformationPaired box protein Pax-3, also known as HuP2, and encoded by the gene name PAX3 or HUP2, is a transcription factor that may be involved in regulating cell proliferation, migration, and apoptosis. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect PAX3 using this Anti-PAX3, clone 7D8G7 Antibody validated for use in western blotting & ELISA.
Key Applications
  • Western Blotting
  • ELISA
Application NotesELISA: A representative lot was used on control antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Biological Information
ImmunogenPurified recombinant fragment of human PAX3 expressed in E. Coli
Clone7D8G7
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Gene Symbol
  • PAX3
  • HUP2
Purification MethodUnpurified
UniProt Number
Molecular Weight~53 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A549, A431, Jurkat, rat spleen, and mouse liver lysates.

Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected PAX3 in A549, A431, Jurkat, rat spleen, and mouse liver lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
MABC699 04053252955334