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528215 Anti-PAI-1 Mouse mAb (MA-33B8)

528215
Purchase on Sigma-Aldrich

概述

重要规格表

Species ReactivityHostAntibody Type
H, RbMMonoclonal Antibody

Products

产品目录编号包装 数量 / 包装
528215-100UGCN 塑胶安瓿;塑胶针药瓶 100 μg
Description
OverviewRecognizes the ~50 kDa PAI-1 protein.
Catalogue Number528215
Brand Family Calbiochem®
SynonymsAnti-Plasminogen Activator Inihibitor-1
References
ReferencesMontes, R., et al. 2000. Thromb. Haemost. 84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.
PreservativeNone
Quality LevelMQ100
Applications
Application ReferencesNeutralization Studies Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
Key Applications Immunoblotting (Western Blotting)
Neutralization Studies
Application NotesImmunoblotting (10 µg/ml)
Neutralization Studies (see application references)
Application CommentsRapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenhuman tPA-PAI-1 complex
ImmunogenHuman
CloneMA-33B8
HostMouse
Purity≥ 90% by SDS-PAGE
IsotypeIgG
Species Reactivity
  • Human
  • Rabbit
Antibody TypeMonoclonal Antibody
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Global Trade Item Number
产品目录编号 GTIN
528215-100UGCN 04055977196511