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AB15510 Anti-Neuroligin 2 Antibody

Anti-Neuroligin 2 Antibody is an antibody against Neuroligin 2 for use in WB, ELISA.

Anti-Neuroligin 2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Synapse & Synaptic Biology Gene Symbol: NLGN2, KIAA1366 UniProt Number: Q8NFZ4
AB15510
50 µg  
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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ELISARbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB15510
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Neuroligin 2 Antibody
Background InformationNeuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
References
Product Information
FormatPurified
PresentationLiquid in PBS with 0.1% BSA.
Quality LevelMQ100
Applications
ApplicationAnti-Neuroligin 2 Antibody is an antibody against Neuroligin 2 for use in WB, ELISA.
Key Applications
  • Western Blotting
  • ELISA
Application NotesWestern blot: 1-10 μg/mL using ECL.
Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 μg/mL
ELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well.
Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenSynthetic peptide near the C-terminus of human Neuroligin 2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityNeuroligin 2 (NLGN2).
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
Gene Symbol
  • NLGN2
  • KIAA1366
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q8NFZ4 # Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures.
SIZE: 835 amino acids; 90820 Da
SUBUNIT: Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts with INADL (By similarity). Probably interacts through its C-terminus with DLG4 third PDZ domain.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
SIMILARITY: SwissProt: Q8NFZ4 ## Belongs to the type-B carboxylesterase/lipase family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
AB15510 04053252476501