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MABC607 Anti-MTSS1 Antibody, clone 15C3.2

Detect MTSS1 using this mouse monoclonal Anti-MTSS1 Antibody, clone 15C3.2, Cat. No. MABC607, validated for use in Western Blotting and Immunohistochemistry (Paraffin).

Anti-MTSS1 Antibody, clone 15C3.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: MTSS1, KIAA0429, MIM UniProt Number: O43312
MABC607
100 μg  
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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MkWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC607
DescriptionAnti-MTSS1 Antibody, clone 15C3.2
Alternate Names
  • Metastasis suppressor protein 1
  • Metastasis suppressor YGL-1
  • Missing in metastasis protein
  • MTSS1
Background InformationMetastasis suppressor protein 1 (UniProt O43312; also known as Metastasis suppressor YGL-1, Missing in metastasis protein) is encoded by the MTSS1 (also known as KIAA0429, MIM) gene (Gene ID 9788) in human. MTSS1 is a scaffold protein that regulates cytoskeletal dynamics and actin polymerization. MTSS1 is also reported to bind Gli proteins or the Gli-Sufu complex and potentiate the transcription of effector genes of the sonic hedgehog signaling pathway. MTSS1 is down-regulated in many metastatic cancer cells compared with their non-metastatic counterparts. MTSS1 expression is shown to be inversely correlated with the prognosis of solid carcinomas of the breast, liver, and bladder.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect MTSS1 using this mouse monoclonal Anti-MTSS1 Antibody, clone 15C3.2, Cat. No. MABC607, validated for use in Western Blotting and Immunohistochemistry (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected MTSS1 in human colon and human spleen tissues.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the C-terminal of human MTSS1.
EpitopeC-terminal
Clone15C3.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityThis clone is expected to react with all 4 spliced isoforms of human MTSS1.
IsotypeIgG2aκ
Species Reactivity
  • Human
  • Monkey
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • MTSS1
  • KIAA0429
  • MIM
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~82 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in COS-1 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected MTSS1 in 10 µg of COS-1 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
MABC607 04055977177053