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05-554-25UG Anti-KDR/Flk-1 Antibody, clone CH-11

Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11 detects level of KDR/Flk-1/VEGFR2 & has been published & validated for use in ELISA, IC & WB.

05-554-25UG
25 μg  
Purchase on Sigma-Aldrich

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概述

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Description
Catalogue Number05-554-25UG
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-KDR/Flk-1 Antibody, clone CH-11
Product Information
FormatPurified
Presentation20mM sodium phosphate, pH 7.6, 250mM NaCl with 0.1% sodium azide
Quality LevelMQ100
Applications
ApplicationAnti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11 detects level of KDR/Flk-1/VEGFR2 & has been published & validated for use in ELISA, IC & WB.
Key Applications
  • ELISA
  • Immunocytochemistry
  • Western Blotting
Biological Information
ImmunogenRecombinant protein corresponding to residues 1158-1345 of murine KDR/Flk-1
Cloneclone CH-11
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityKDR/Flk-1
IsotypeIgG1
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • KDR
  • VEGFR-2
  • VEGFR2
  • VEGFR
  • CD309
  • FLK1
Purification MethodProtein A chromatography
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
SIZE: 1356 amino acids; 151527 Da
SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight230kDa
Product Usage Statements
Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from HUVEC cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at 4°C
Packaging Information
Material Size25 μg
Global Trade Item Number
产品目录编号 GTIN
05-554-25UG 04054839342394