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MABS809 Anti-JAK2, clone 1C1 Antibody

Anti-JAK2, clone 1C1 Antibody is an antibody against JAK2 for use in Western Blotting.

Anti-JAK2, clone 1C1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: JAK2 UniProt Number: O60674
MABS809
100 µL  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

特卖

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABS809
Replaces04-1098
DescriptionAnti-JAK2, clone 1C1 Antibody
Alternate Names
  • Tyrosine-protein kinase JAK2
  • JAK2
Background InformationTyrosine-protein kinase JAK2 (JAK2) belongs to the protein kinase superfamily. JAK2 is involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Mutations in JAK2 have been associated with Budd-Chiari syndrome and Polycythemia vera.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1ascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-JAK2, clone 1C1 Antibody is an antibody against JAK2 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of JAK2 expressed in E. Coli
Clone1C1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • JAK2
Purification MethodUnpurified
UniProt Number
Molecular Weight~129 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected JAK2 in THP-1 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
MABS809 04055977172201