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ABS111 Anti-Fidgetin Antibody

ABS111
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS111
DescriptionAnti-Fidgetin Antibody
Background InformationFidgetin is a AAA protein that belongs to the meitoic or subfamily-7 (SF7) group of ATPases. These enzymes are associated with many different general cellular activities, such as but not limited to, membrane fusion, proteolysis, metabolic signaling, peroxisome biogenesis, endosome sorting, and meiotic spindle formation. However, the specific functions and mechanisms for SF7 AAA proteins remain largely unclear. It is reported that mutant Fidgetin is found in a mammalian developmental mutant and is suggested to play in role in embryonic development.
References
Product Information
FormatAffinity Purified
Control
  • Mouse brain tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Fidgetin Antibody is an antibody against Fidgetin for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern Blot Analysis: 1 µg/mL from a representative lot detected Figetin in U20S cell lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Fidgetin.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Mouse
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FIGN
Purification MethodAffinity Purfied
UniProt Number
UniProt SummarySUBCELLULAR STRUCTURE: Interacts with AKAP8 (via C-terminus).

SUBCELLULAR LOCATION: Nucleus matrix.
Molecular Weight~60 kDa observed.
The calculated molecular weight of this protein is 82 kDa, but is observed at ~60 kDa due to a splice variant (Yang, Y., et al. (2005). Experimental Cell Research. 304:50-58).
Uncharacterized bands may be observed at ~25 kDa and ~57 kDa in some tissue lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Figetin in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABS111 04053252755095