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ABN428 Anti-Fezf2 Antibody

ABN428
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN428
DescriptionAnti-Fezf2 Antibody
Alternate Names
  • Fez family zinc finger protein 2
  • Forebrain embryonic zinc finger-like protein 2
  • Zinc finger protein 312
  • Zinc finger protein Fez-like
Background InformationFezf2 is a transcriptional repressor protein. It is required for the specification of corticospinal motor neurons and other subcerebral projection neurons. FeZf2 also plays a role in the layer and subcortical specific patterning of the subcortical projections and axonal fasciculations that develop in the brain. Fezf2 also controls the development of the dendritic arborization and spines of the large layer V pyramidal neurons. Thus biological processes involving Fezf2 include neuronal patterning, differentiation, neurogenesis, axon guidance, fasciculation, cortex development, anterior/posterior patterning, dendrite development, and locomotory behavior, and it was recently identified as a multipotent progenitor marker for neocortical projection neurons, astrocytes, and oligodendrocytes.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fezf2 in rat spinal cord tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the Engrailed homology 1 repressor domain of human Fezf2.
EpitopeEngrailed homology 1 repressor domain
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FEZF2
  • FEZL
  • ZNF312
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~50 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse E13-14 brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Fezf2 in 10 µg of mouse E13-14 brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN428 04053252986475