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MABF1566 Sigma-AldrichAnti-CD4 (Mouse), APC, clone RM4-5 Antibody

This Anti-CD4 (Mouse), APC, clone RM4-5 Antibody is validated for use in Flow Cytometry for the detection of CD4.

Anti-CD4 (Mouse), APC, clone RM4-5 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子
Posters

Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Cd4 UniProt Number: P06332

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
M	FC	R	APC	Monoclonal Antibody

Description
Catalogue Number	MABF1566
Description	Anti-CD4 (Mouse), APC, clone RM4-5 Antibody
Alternate Names	T-cell surface glycoprotein CD4 T-cell differentiation antigen L3T4 T-cell surface antigen T4/Leu-3 CD4 CD4
Background Information	The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the RM4-5 antibody and an alternative antibody, Anti-Mouse CD4 clone GK1.5, will “compete” for binding, i.e. RM4-5 antibody is able to block GK1.5 antibody binding to cells. In contrast, RM4-5 antibody does not block the binding of Anti-Mouse CD4 clone RM4-4 to cells.

References

Product Information
Format	APC
Presentation	Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Quality Level	MQ100

Applications
Application	This Anti-CD4 (Mouse), APC, clone RM4-5 Antibody is validated for use in Flow Cytometry for the detection of CD4.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Immunogen information for this antibody is proprietary information.
Clone	RM4-5
Concentration	Please refer to lot specific datasheet.
Host	Rat
Isotype	IgG2aκ
Species Reactivity	Mouse
Antibody Type	Monoclonal Antibody
Gene Symbol	Cd4
Purification Method	Purified by size-exclusion chromatography
UniProt Number	P06332

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD4 in one million C57Bl/6 splenocytes.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Packaging Information
Material Size	100 μg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABF1566	04055977292725

Documentation

Anti-CD4 (Mouse), APC, clone RM4-5 Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-CD4 (Mouse), APC, clone RM4-5 Antibody 分析证书

标题	批号
Anti-CD4 (Mouse), APC, clone RM4-5 - VP1901102	VP1901102
Anti-CD4 (Mouse), APC, clone RM4-5 - VP1902202	VP1902202
Anti-CD4 (Mouse), APC, clone RM4-5 -VP1505067	VP1505067
Anti-CD4 (Mouse), APC, clone RM4-5 Monoclonal Antibody	VP1803202

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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