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ABC1480 Anti-BCL6 Antibody

This Anti-BCL6 Antibody is validated for use in Western Blotting for the detection of BCL6.

Anti-BCL6 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: BCL6, BCL5, LAZ3, ZBTB27, ZNF51 UniProt Number: P41182
ABC1480
100 μg  
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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC1480
Replaces04-437
DescriptionAnti-BCL6 Antibody
Alternate Names
  • B-cell lymphoma 6 protein
  • BCL-6
  • B-cell lymphoma 5 protein
  • BCL-5
  • Protein LAZ-3
  • Zinc finger and BTB domain-containing protein 27
  • Zinc finger protein 51
  • BCL6
Background InformationBCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Quality LevelMQ300
Applications
ApplicationThis Anti-BCL6 Antibody is validated for use in Western Blotting for the detection of BCL6.
Key Applications
  • Western Blotting
Biological Information
ImmunogenBCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.
EpitopeNear Center
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Gene Symbol
  • BCL6
  • BCL5
  • LAZ3
  • ZBTB27
  • ZNF51
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~68 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in rat lung tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected BCL6 in 15 µg of rat lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABC1480 04055977174533