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07-2178 Anti-Abl interactor 1 Antibody

Detect Abl interactor 1 using this Anti-Abl interactor 1 Antibody validated for use in Western Blotting.

Anti-Abl interactor 1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: ABI1, SSH3BP1 UniProt Number: Q8IZP0
07-2178
100 µL  
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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number07-2178
DescriptionAnti-Abl interactor 1 Antibody
Alternate Names
  • Abl interactor 1
  • Abelson interactor 1
  • Abi-1
  • Abl-binding protein 4
  • AblBP4
  • Eps8 SH3 domain-binding protein
  • Eps8-binding protein
  • Nap1-binding protein
  • Nap1BP
  • Spectrin SH3 domain-binding protein 1
  • e3B1
Background InformationAbl interactor 1 (Abelson interactor 1) is a member of the family of Abl-interactors and is highly expressed in the brain. Abl interactor 1 is involved in the signaling of ABL1 and ABL2 nonreceptor tyrosine kinases, and the EGF-receptor. The Abl interactor 1 protein contains SH3 domains, and may function as an adaptor protein; It forms a trimeric complex with EPS8 and SOS1 in the transduction of signals from Ras to Rac. Previous studies have suggested that Abl interactor 1 via the Ras and Rac pathways may regulate cell proliferation, cell adhesion, and actin remodeling. Abl interactor 1 is also investigated for its role in tumor suppression.
References
Product Information
FormatAffinity Purified
Control
  • Jurkat cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Abl interactor 1 using this Anti-Abl interactor 1 Antibody validated for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Abl interactor 1.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteDemonstrated to react with Human and Mouse. Predicted to react with Rat and Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ABI1
  • SSH3BP1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~60 kDa observed. Uniprot describes many isoforms between 43-55 kDa that can be highly phosphorylated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in Jurkat cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Abl interactor 1 on 10 µg of Jurkat cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
07-2178 04053252648144