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ABN479 Anti-ATP2C1 Antibody

ABN479
100 µg  
Purchase on Sigma-Aldrich

特卖

概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN479
DescriptionAnti-ATP2C1 Antibody
Alternate Names
  • Calcium-transporting ATPase type 2C member 1
  • ATPase 2C1
  • ATP-dependent Ca(2+) pump PMR1
  • ATP2C1
Background InformationCalcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes.
References
Product Information
FormatAffinity Purified
Control
  • Mouse brain tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected ATP2C1 in mouse brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human ATP2C1.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa.
Species Reactivity
  • Mouse
Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • ATP2C1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected ATP2C1 in 15 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
ABN479 04053252905513