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176872 Angiotensin Converting Enzyme-2, His•Tag®, Human, Recombinant, NSO Cells

176872
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概述

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产品目录编号包装 数量 / 包装
176872-10UGCN 玻璃瓶 10 μg
Description
OverviewRecombinant, human ACE-2 ectodomain (amino acids 1-740) fused at the C-terminus to a His•Tag® sequence and expressed in NSO cells. Native ACE-2 is an integral membrane zinc metalloprotease that can be inhibited by EDTA. ACE-2 cleaves angiotensins I and II. Plays an important role in regulating cardiovascular and renal functions. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing condition.
Catalogue Number176872
Brand Family Calbiochem®
SynonymsACE Homolog, ACEH, ACE-2
References
ReferencesTikellis, C., et al. 2003. Hypertension 41, 390.
Tipnis, S.R., et al. 2000. J. Biol. Chem. 275, 33238.
Product Information
Unit of DefinitionOne unit is defined as the amount of enzyme that will cleave 1 nmol MCA-YVADAPK(DNP)-OH per min at 25°C, pH 7.5.
FormLiquid
Quality LevelMQ100
Biological Information
Purity≥90% by SDS-PAGE
Specific Activity≥0.8 unit/µg protein
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsEndotoxins: ≤1.0 EU/µg ACE-2
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
产品目录编号 GTIN
176872-10UGCN 04055977222999