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178251 Sigma-Aldrichα₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem

α₁-Antitrypsin, CAS 9041-92-3, is a protease inhibitor of the serpin superfamily. Inhibits elastase, cathepsin G, and proteinase 3.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: α₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein

Recommended Products

概述

Replacement Information

重要规格表

CAS #
9041-92-3

Products

产品目录编号	包装	数量 / 包装
178251-1MGCN	玻璃瓶	1 mg	添加到收藏夹添加到收藏夹添加到我的收藏夹
178251-5MGCN	塑胶安瓿;塑胶针药瓶	5 mg	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase. Inhibitor of neutrophil elastase, cathepsin G, and proteinase 3.
Catalogue Number	178251
Brand Family	Calbiochem®
Synonyms	α₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein

References
References	Coakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33. Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.

Product Information
CAS number	9041-92-3
Activity	≥75% inhibition with active-site titrated porcine trypsin using benzoyl-Arg-p-nitroanilide (Bz-Arg-pNA) as the substrate.
ATP Competitive	N
Form	Solid
Formulation	Lyophilized from 300 mM NaCl, 30 mM sodium phosphate buffer, pH 6.5.
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	serine proteases
Purity	≥95% by SDS-PAGE
Source	Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
178251-1MGCN	07790788059835
178251-5MGCN	04055977223132

Documentation

α₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

α₁-Antitrypsin, Human Plasma - CAS 9041-92-3 - Calbiochem 分析证书

标题	批号
178251	输入批号

参考

参考信息概述
Coakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33. Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	15-April-2008 RFH
Synonyms	α₁-AT, α₁-Proteinase Inhibitor, 3.5S α₁-Glycoprotein
Description	A single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues. Present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase.
Form	Solid
Formulation	Lyophilized from 300 mM NaCl, 30 mM sodium phosphate buffer, pH 6.5.
Source	Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number	9041-92-3
Purity	≥95% by SDS-PAGE
Activity	≥75% inhibition with active-site titrated porcine trypsin using benzoyl-Arg-p-nitroanilide (Bz-Arg-pNA) as the substrate.
Solubility	H₂O. Please refer to vial label for lot-specific volume prior to lyophilization.
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Toxicity	Standard Handling
Merck USA index	14, 719
References	Coakley, R.J., et al. 2001. Am. J. Med. Sci. 321, 33. Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem. 52, 655.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Elastase Inhibitors

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors

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