565740 Sigma-Aldrichα-Amyloid Precursor Protein Modulator - CAS 497259-23-1 - Calbiochem
A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas
More>> A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: (2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam, PKC Activator V
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概述
重要规格表
CAS # | Empirical Formula |
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497259-23-1 | C₂₇H₃₀F₃N₃O₃ |
Products
产品目录编号 | 包装 | 数量 / 包装 | |
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565740-1MGCN | 塑胶安瓿;塑胶针药瓶 | 1 mg |
References | |
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References | Kozikowski, A.P., et al. 2003. J. Med. Chem. 46, 364. |
Product Information | |
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CAS number | 497259-23-1 |
ATP Competitive | N |
Form | Orange solid |
Hill Formula | C₂₇H₃₀F₃N₃O₃ |
Chemical formula | C₂₇H₃₀F₃N₃O₃ |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | PKC |
Primary Target K<sub>i</sub> | 11.9 nM for activating PKCα |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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产品目录编号 | GTIN |
565740-1MGCN | 04055977267648 |