Histone Peptide Arrays |
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| AbSurance™ Histone Antibody Specificity Arrays  Learn More about AbSurance™ Histone Antibody Specificity Arrays Start Screening |
NEW! AbSurance™ Pro Histone Peptide Microarray
Within chromatin, the accessible regions of histones represent substrates for chromatin writer and eraser enzymes, as well as recognition domains for chromatin reader proteins that facilitate higher order structure important in chromatin, gene and nuclear regulation.The AbSurance™ Pro Histone Peptide Microarray is a glass microarray containing peptides corresponding to sequences of all four core histone subunits (H2A, H2B, H3, H4) plus select variants. Over 260 histone peptides representing various post-translational modifications are present on the array as unmodified, singly modified as well as multiply modified sequences with up to six modifications per peptide. Each Microarray is printed as two subarrays (see figure 2) with each peptide represented six times per subarray to ensure confident binding analysis and quantitation.
Applications
- Interaction analysis of histone readers, writers and erasers
- Histone Antibody Specificity Screening
- See Peptide List on product page
- Learn How to use the Array
 Alternatively, to assess specificity of a histone antibody, you need a primary antibody to a histone modification and a fluorescently-labeled secondary antibody recognizing the primary antibody. The entire procedure is similar to the one employed in immunofluorescence microscopy. Click image to enlarge. |
 Detailed information about the exact position of each peptide can be found in the Excel spreadsheet “AbSurance Pro Peptides.xlsx” available on our website. Click image to enlarge. |
Histone Antibody Specific Arrays