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137042 tri-Sodium citrate dihydrate cryst.

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3200-675-3C₆H₅Na₃O₇ * 2 H₂O294.10 g/molPh Eur,BP,JP,USP,ACS

Products

Catalogue NumberPackaging Qty/Pack
1.37042.0001 Fibre case 3 x 1 kg
Description
Catalogue Number137042
SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
References
Product Information
CAS number6132-04-3
EC number200-675-3
GradePh Eur,BP,JP,USP,ACS
Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
Molar Mass294.10 g/mol
HS Code2918 15 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Melting Point300 °C (anhydrous substance)
pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density600 kg/m3
Solubility720 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 8000 mg/kg
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur))99.0 - 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP)99.0 - 100.5 %
Identity (Na)passes test
Identity (Citrate)passes test
Identity (reaction upon ignition)passes test
Appearancewhite crystals
Appearance of solution (100 g/l, CO₂-free water)clear and colorless
Acidity or alkalinitypasses test
pH (50 g/l CO₂-free water)7.5 - 8.5
In water insoluble matter #≤ 50 ppm
Chloride (Cl)≤ 30 ppm
Sulfate (SO₄)≤ 50 ppm
Heavy metals (as Pb)≤ 5 ppm
Al (Aluminium)≤ 5 ppm
As (Arsenic)≤ 2 ppm
NH4 (Ammonium) #≤ 30 ppm
Ca (Calcium) #≤ 50 ppm
Fe (Iron) #≤ 5 ppm
Oxalate (as C₂H₂O₄)≤ 300 ppm
Tartrate (C₄H₄O₆)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Readily carbonisable substancepasses test
Water (according to Karl Fischer)11.0 - 13.0 %
Loss on drying (180 °C, 18 h)10.0 - 13.0 %
Total aerobic microbial count (TAMC)≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
Candida albicans (absent in 1 g)passes test
Escherichia coli (absent in 1 g)passes test
Pseudomonas aeruginosa (absent in 1 g)passes test
Salmonella (absent in 10 g)passes test
Staphylococcus aureus (absent in 1 g)passes test
Bacterial endotoxins≤ 2.5 I.U./g
# Additional requirements by ACS
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP, ACS
Global Trade Item Number
Catalogue Number GTIN
1.37042.0001 04054839001376

Documentation

Quality Management Dossier (Open Access)

Title

tri-Sodium citrate dihydrate cryst. SDS

Title

Safety Data Sheet (SDS) 

tri-Sodium citrate dihydrate cryst. Certificates of Analysis

Product Number PackagingSpecificationLot Number
1.37042.0001 Fibre casePDF Specification Document

Certificates

Title