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516705
Sigma-Aldricho-Phenanthroline - CAS 5144-89-8 - Calbiochem
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.
More>>A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a metalloprotease inhibitor. Inhibits glioma invasion in vitro.
Catalogue Number
516705
Brand Family
Calbiochem®
Synonyms
1,10-Phenanthroline Monohydrate
References
References
Stix, B., et al. 2001. Am. J. Pathol.159, 561. Bolzan, A.D., et al. 2000. Mutat. Res.447, 221. Wang, Y., et al. 1999. J. Biol. Chem.274, 33043. Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942. Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509. Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.
Toxic if swallowed. Very toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
S Phrase
S: 45-60-61-37
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). This material and its container must be disposed of as hazardous waste. Avoid release to the environment. Refer to special instructions/safety data sheet. Wear suitable gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+15°C to +30°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 3 months at 4°C.
o-Phenanthroline - CAS 5144-89-8 - Calbiochem Certificates of Analysis
Title
Lot Number
516705
References
Reference overview
Stix, B., et al. 2001. Am. J. Pathol.159, 561. Bolzan, A.D., et al. 2000. Mutat. Res.447, 221. Wang, Y., et al. 1999. J. Biol. Chem.274, 33043. Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942. Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509. Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
27-August-2018 JSW
Synonyms
1,10-Phenanthroline Monohydrate
Description
A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a general matrix metalloproteinase inhibitor. Forms a red chelate with Fe2+ that absorbs maximally at 510 nm. Can be used as a photometric reagent for iron.
Form
White to cream solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
5144-89-8
RTECS
SF8437000
Chemical formula
C₁₂H₈N₂ · H₂O
Structure formula
Purity
≥99% by titration
Solubility
DMSO (100 mg/ml), ethanol (25 mg/ml), or H₂O (3 mg/ml)
Storage
Protect from light +15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 3 months at 4°C.
Toxicity
Toxic
Merck USA index
14, 7214
References
Stix, B., et al. 2001. Am. J. Pathol.159, 561. Bolzan, A.D., et al. 2000. Mutat. Res.447, 221. Wang, Y., et al. 1999. J. Biol. Chem.274, 33043. Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942. Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509. Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.
