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681525 Wiskostatin - CAS 253449-04-6 - Calbiochem

681525
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Overview

Key Spec Table

CAS #Empirical Formula
253449-04-6C₁₇H₁₈Br₂N₂O

Products

Catalogue NumberPackaging Qty/Pack
681525-1MGCN Plastic ampoule 1 mg
681525-5MGCN Plastic ampoule 5 mg
Description
OverviewA cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. Acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Appears to bind to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
Catalogue Number681525
Brand Family Calbiochem®
References
ReferencesPeterson, J.R., et al. 2004. Nat. Struct. Mol. Biol. 11, 747.
Peterson, J.R., and Mitchison, T.J. 2002. Chem. Biol. 9, 1275.
Product Information
CAS number253449-04-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₇H₁₈Br₂N₂O
Chemical formulaC₁₇H₁₈Br₂N₂O
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetN-WASP (neural Wiskott Aldrich syndrome protein)
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
681525-1MGCN 04055977260090
681525-5MGCN 04055977260106