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625625 Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-O-α-D-Glucopyranosyl-α-D-glucopyranoside

625625
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
6138-23-4C₁₂H₂₂O₁₁ · 2H₂O

Products

Catalogue NumberPackaging Qty/Pack
625625-1KGCN Glass bottle 1 kg
625625-50GMCN Glass bottle 50 gm
Description
OverviewNon-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
Catalogue Number625625
Brand Family Calbiochem®
Synonyms1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
References
ReferencesSarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med. 10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
Product Information
CAS number6138-23-4
FormSolid
Hill FormulaC₁₂H₂₂O₁₁ · 2H₂O
Chemical formulaC₁₂H₂₂O₁₁ · 2H₂O
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥97.5% by Assay
Physicochemical Information
ContaminantsHeavy metals: <10 ppm; iron: <5 ppm
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
S PhraseS: 24/25-37-45

Avoid contact with skin and eyes.
Wear suitable gloves.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
625625-1KGCN 04055977262728
625625-50GMCN 07790788051976

Documentation

Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem Certificates of Analysis

TitleLot Number
625625

References

Reference overview
Sarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med. 10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-April-2010 JSW
Synonyms1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
DescriptionNon-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
FormSolid
CAS number6138-23-4
Chemical formulaC₁₂H₂₂O₁₁ · 2H₂O
Structure formulaStructure formula
Purity≥97.5% by Assay
ContaminantsHeavy metals: <10 ppm; iron: <5 ppm
SolubilityH₂O (100 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Toxicity Standard Handling
Merck USA index14, 9580
ReferencesSarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med. 10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.