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605160 Thrombin, Plasminogen-Free, Bovine

Thrombin, Plasminogen-Free, Bovine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
605160
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
605160-1KUCN Plastic ampoule 1 ku
Description
OverviewNative, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Note: 1 KU = 1000 units.
Catalogue Number605160
Brand Family Calbiochem®
References
Product Information
CAS number9002-04-4
Unit of DefinitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
FormLyophilized
FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
Quality LevelMQ100
Applications
Biological Information
PurityComplete activation from homogeneous bovine prothrombin by SDS-PAGE
Specific Activity≥1000 NIH units/mg protein
Physicochemical Information
ContaminantsPlasminogen: none detected by rocket IEP
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSXO8950000
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
605160-1KUCN 04055977188370

Documentation

Thrombin, Plasminogen-Free, Bovine SDS

Title

Safety Data Sheet (SDS) 

Thrombin, Plasminogen-Free, Bovine Certificates of Analysis

TitleLot Number
605160
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-May-2008 RFH
DescriptionNative, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Serine protease formed in the plasma during the coagulation process by activation of prothrombin by a complex of Factor Xa, Factor Va, phospholipid, and Ca2+. Thrombin cleaves Arg-Gly bonds in specific sequences only. The best characterized activity of thrombin is the conversion of fibrinogen to fibrin in the clotting process. Inhibited by AEBSF (Cat. No. 101500) Antithrombin (Cat. No. 169756), PMSF (Cat. No. 52332), and TLCK (Cat. No. 616382). Note: 1 KU = 1000 units.
FormLyophilized
FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
CAS number9002-04-4
RTECSXO8950000
PurityComplete activation from homogeneous bovine prothrombin by SDS-PAGE
ContaminantsPlasminogen: none detected by rocket IEP
Specific activity≥1000 NIH units/mg protein
Unit definitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
SolubilityH₂O (1 mg/ml)
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Toxicity Harmful
Merck USA index14, 9383