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584222 Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
584222
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
18771-50-1C₉H₁₆N₂O₆

Products

Catalogue NumberPackaging Qty/Pack
584222-10MGCN Plastic ampoule 10 mg
Description
OverviewPotent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O(Cat. No. 584223).
Catalogue Number584222
Brand Family Calbiochem®
References
ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
Riva, C., et al. 1992. Chemotherapy 38, 358.
Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
Product Information
CAS number18771-50-1
FormWhite to off-white solid
Hill FormulaC₉H₁₆N₂O₆
Chemical formulaC₉H₁₆N₂O₆
Hygroscopic Hygroscopic
Quality LevelMQ100
Applications
Biological Information
Purity≥90% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSUW5798980
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
584222-10MGCN 04055977264944

Documentation

Tetrahydrouridine - CAS 18771-50-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Certificates of Analysis

TitleLot Number
584222

References

Reference overview
Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
Riva, C., et al. 1992. Chemotherapy 38, 358.
Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-June-2013 JSW
DescriptionA potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.
FormWhite to off-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number18771-50-1
RTECSUW5798980
Chemical formulaC₉H₁₆N₂O₆
Purity≥90% by TLC
SolubilityH₂O (200 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesYusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857.
Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7.
Riva, C., et al. 1992. Chemotherapy 38, 358.
Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.