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575307 T113242 - CAS 195533-44-9 - Calbiochem

A cell-permeable pentafluorosulfonamide compound that induces microtubule depolymerization and cell-cycle arrest by irreversibly modifying β-tubulin.

T113242 - CAS 195533-44-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: T1, (4-N,Nʹ-Dimethylanilino)-pentafluorosulfonamide

Primary Target: β-tubulin
575307
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
195533-44-9C₁₄H₁₁F₅N₂O₂S

Products

Catalogue NumberPackaging Qty/Pack
575307-10MGCN Plastic ampoule 10 mg
Description
OverviewA cell-permeable pentafluorosulfonamide compound that induces microtubule depolymerization and cell-cycle arrest by irreversibly modifying β-tubulin. T113242-induced activation of gene transcriptions has been shown to be mediated by Erk signalling pathway and the transcription factor MIZ-1 (myc-interacting zinc finger protein).
Catalogue Number575307
Brand Family Calbiochem®
SynonymsT1, (4-N,Nʹ-Dimethylanilino)-pentafluorosulfonamide
References
ReferencesZiegelbauer, J., et al. 2004. Proc. Natl. Acad. Sci. USA 101, 458.
Ziegelbauer, J., et al. 2001. Mol. Cell 8, 339.
Product Information
CAS number195533-44-9
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₄H₁₁F₅N₂O₂S
Chemical formulaC₁₄H₁₁F₅N₂O₂S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetβ-tubulin
Purity≥90% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
575307-10MGCN 04055977189247

Documentation

T113242 - CAS 195533-44-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

T113242 - CAS 195533-44-9 - Calbiochem Certificates of Analysis

TitleLot Number
575307

References

Reference overview
Ziegelbauer, J., et al. 2004. Proc. Natl. Acad. Sci. USA 101, 458.
Ziegelbauer, J., et al. 2001. Mol. Cell 8, 339.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-October-2010 RFH
SynonymsT1, (4-N,Nʹ-Dimethylanilino)-pentafluorosulfonamide
DescriptionA cell-permeable pentafluorosulfonamide compound that covalently binds to β-tubulin and induces microtubule depolymerization and cell-cycle arrest by irreversibly modifying β-tubulin. T113242-induced activation of gene transcription has been shown to be mediated by the Erk signaling pathway and the transcription factor MIZ-1 (myc-interacting zinc finger protein).
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number195533-44-9
Chemical formulaC₁₄H₁₁F₅N₂O₂S
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityDMSO (200 mg/ml) or Methanol (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
ReferencesZiegelbauer, J., et al. 2004. Proc. Natl. Acad. Sci. USA 101, 458.
Ziegelbauer, J., et al. 2001. Mol. Cell 8, 339.