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100631 Salicylic acid

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
69-72-7200-712-3C₇H₆O₃HOC₆H₄COOH138.12 g/molPh Eur,BP,USP

Products

Catalogue NumberPackaging Qty/Pack
1.00631.1000 Plastic bottle 1 kg
1.00631.9024 Double PE Sack 20 kg
Description
Catalogue Number100631
Synonyms2-Hydroxybenzoic acid
DescriptionSalicylic acid
References
Product Information
CAS number69-72-7
EC number200-712-3
GradePh Eur,BP,USP
Hill FormulaC₇H₆O₃
Chemical formulaHOC₆H₄COOH
Molar Mass138.12 g/mol
HS Code2918 21 10
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point211 °C (1013 hPa)
Density1.44 g/cm3 (20 °C)
Flash point157 °C
Ignition temperature500 °C
Melting Point158 - 160 °C
pH value2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure1 hPa (114 °C)
Bulk density400 - 500 kg/m3
Solubility2 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 1250 - 1580 mg/kg
LD 50 dermalLD50 Rat > 2000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H302: Harmful if swallowed.
H318: Causes serious eye damage.
H361d: Suspected of damaging the unborn child.
Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
Signal WordDanger
RTECSVO0525000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerharmful, irritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (acidimetric; calculated on dried substance)99.5 - 100.5 %
Assay (HPLC, calc.on dried substance)98.0 - 102.0 %
Identitypasses test
Appearance of solution (10 %; ethanol 96 %)passes test
Chloride (Cl)≤ 0.0100 %
Sulfate (SO₄)≤ 0.0200 %
Related substances / HPLC (EP) (4-Hydroxybenzoic acid)≤ 0.1 %
Related substances / HPLC (EP) (4-Hydroxyisophthalic acid)≤ 0.05 %
Related substances / HPLC (EP) (Phenol)≤ 0.02 %
Related substances / HPLC (EP) (Largest unspecified impurity)≤ 0.05 %
Related substances / HPLC (EP) (Sum of all impurities)≤ 0.2 %
Related substances / HPLC (USP) (4-Hydroxybenzoic acid)≤ 0.1 %
Related substances / HPLC (USP) (4-Hydroxyisophthalic acid)≤ 0.05 %
Related substances / HPLC (USP) (Phenol)≤ 0.02 %
Related substances / HPLC (USP) (Largest unspecified impurity)≤ 0.05 %
Related substances / HPLC (USP) (Sum of all impurities)≤ 0.2 %
Residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash≤ 0.05 %
Loss on drying≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
corresponds to Ph Eur, BP, USP
Global Trade Item Number
Catalogue Number GTIN
1.00631.1000 04022536008554
1.00631.9024 04022536979212

Documentation

Material Qualification Dossier

TitleVersion
7.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Salicylic acid SDS

Title

Safety Data Sheet (SDS) 

Salicylic acid Certificates of Analysis

Product Number PackagingSpecificationLot Number
1.00631.1000 Plastic bottlePDF Specification Document
1.00631.9024 Double PE SackPDF Specification Document

Certificates

Title

Application Notes

Title
Water in Ammonia, aqueous