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14-581M Ron Protein, active, 250 µg

Active, N-terminal GST-tagged, recombinant, human Ron amino acids 983-end, for use in Kinase Assays.

Ron Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-581M
250 µg  Also available in 10 μg size (cat#14-581) and in bulk (cat# 14-581-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-581M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionRon Protein, active, 250 µg
OverviewN-terminal GST-tagged, recombinant, human Ron amino acids 983-end
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal GST-tagged, recombinant, human Ron amino acids 983-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Gene Symbol
  • MST1R
  • CDw136
  • RON
  • PTK8
  • p185-Ron
Protein TargetRon
Purification MethodGlutathione agarose affinity chromatography
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q04912 # Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
SIZE: 1400 amino acids; 152227 Da
SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Keratinocytes and lung.
PTM: Proteolytic processing yields the two subunits. & Phosphorylated in response to ligand binding (Probable).
SIMILARITY: SwissProt: Q04912 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. & Contains 3 IPT/TIG domains. & Contains 1 protein kinase domain. & Contains 1 Sema domain.
Molecular Weight74.2kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylating Axltide (Catalog #12-516)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-581) and in bulk (cat# 14-581-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-581M 04053252590009

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-581 Ron Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases