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551826 QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem

Binding of Ca2+ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K

551826
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
73630-23-6C₂₆H₂₃N₃O₁₀ · 4K

Products

Catalogue NumberPackaging Qty/Pack
551826-50MGCN Plastic ampoule 50 mg
Description
OverviewBinding of Ca2+ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells.
Catalogue Number551826
Brand Family Calbiochem®
Synonyms2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K
References
ReferencesKomada, H., et al. 1989. Cell Struct. Funct. 14, 141.
Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
Bryant, D.T. 1985. Biochem. J. 226, 613.
Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
Ashley R.H., et al. 1984. Biochem. J. 219, 149.
Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
Tsien, R.Y. 1980. Biochemistry 19, 2396.
Product Information
CAS number73630-23-6
ATP CompetitiveN
FormYellow solid
Hill FormulaC₂₆H₂₃N₃O₁₀ · 4K
Chemical formulaC₂₆H₂₃N₃O₁₀ · 4K
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCalcium Probes
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas, pH >10. Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
551826-50MGCN 04055977268270

Documentation

QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem Certificates of Analysis

TitleLot Number
551826

References

Reference overview
Komada, H., et al. 1989. Cell Struct. Funct. 14, 141.
Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
Bryant, D.T. 1985. Biochem. J. 226, 613.
Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
Ashley R.H., et al. 1984. Biochem. J. 219, 149.
Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
Tsien, R.Y. 1980. Biochemistry 19, 2396.

Brochure

Title
Fluorescent Calcium Probes Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-July-2010 JSW
Synonyms2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K
DescriptionBinding of Ca2+ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).
FormYellow solid
CAS number73630-23-6
Chemical formulaC₂₆H₂₃N₃O₁₀ · 4K
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (10 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas, pH >10. Stock solutions are stable for up to 6 months at -20°C.
Toxicity Irritant
ReferencesKomada, H., et al. 1989. Cell Struct. Funct. 14, 141.
Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
Bryant, D.T. 1985. Biochem. J. 226, 613.
Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
Ashley R.H., et al. 1984. Biochem. J. 219, 149.
Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
Tsien, R.Y. 1980. Biochemistry 19, 2396.