527455 Sigma-AldrichPKR Inhibitor, Negative Control - CAS 852547-30-9 - Calbiochem
The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: RNA-Dependent Protein Kinase Inhibitor, Negative Control, 5-Chloro-3-(3,5-dichloro-4-hydroxybenzylidene)-1,3-dihydro-indol-2-one
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 852547-30-9 | C₁₅H₈Cl₃NO₂ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 527455-10MGCN | Glass bottle | 10 mg |
| Description | |
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| Overview | An oxindole compound that serves as a negative control for PKR Inhibitor (Cat. No. 527450). Shown to be inactive in inhibiting RNA-induced PKR autophosphorylation (IC50 > 100 µM) or in rescuing PKR-dependent translation block. |
| Catalogue Number | 527455 |
| Brand Family | Calbiochem® |
| Synonyms | RNA-Dependent Protein Kinase Inhibitor, Negative Control, 5-Chloro-3-(3,5-dichloro-4-hydroxybenzylidene)-1,3-dihydro-indol-2-one |
| References | |
|---|---|
| References | Jammi, N.V., et al. 2003. Biochem. Biophys. Res. Commun. 308, 50. |
| Product Information | |
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| CAS number | 852547-30-9 |
| ATP Competitive | N |
| Form | Yellow solid |
| Hill Formula | C₁₅H₈Cl₃NO₂ |
| Chemical formula | C₁₅H₈Cl₃NO₂ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | A negative control for PKR Inhibitor |
| Purity | ≥95% by HPLC (sum of two isomers) |
| Physicochemical Information | |
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| Cell permeable | N |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 527455-10MGCN | 04055977270389 |
Documentation
PKR Inhibitor, Negative Control - CAS 852547-30-9 - Calbiochem SDS
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PKR Inhibitor, Negative Control - CAS 852547-30-9 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 527455 |
References
| Reference overview |
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| Jammi, N.V., et al. 2003. Biochem. Biophys. Res. Commun. 308, 50. |