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490070 Nitric Oxide Synthase, Neuronal Inhibitor I - CAS 357965-99-2 - Calbiochem

490070
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
357965-99-2C₈H₂₁N₇O₂ · 3TFA · 2H₂O

Products

Catalogue NumberPackaging Qty/Pack
490070-5MGCN Plastic ampoule 5 mg
Description
OverviewA cell-permeable, potent and highly selective inhibitor of neuronal nitric oxide synthase (nNOS); (Ki = 120 nM). Displays >2500-fold and 320-fold selectivity over eNOS and iNOS, respectively.
Catalogue Number490070
Brand Family Calbiochem®
Synonyms(4S)-N-(4-Amino-5[aminoethyl]aminopentyl)-Nʹ-nitroguanidine, TFA
References
ReferencesHah, J.M., et al. 2001. J. Med. Chem. 44, 2667.
Product Information
CAS number357965-99-2
ATP CompetitiveN
FormWhite to off-white solid
FormulationSupplied as a dihydrate.
Hill FormulaC₈H₂₁N₇O₂ · 3TFA · 2H₂O
Chemical formulaC₈H₂₁N₇O₂ · 3TFA · 2H₂O
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetnNOS
Primary Target K<sub>i</sub>120 nM against nNOS
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
490070-5MGCN 04055977273410

Documentation

Nitric Oxide Synthase, Neuronal Inhibitor I - CAS 357965-99-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Nitric Oxide Synthase, Neuronal Inhibitor I - CAS 357965-99-2 - Calbiochem Certificates of Analysis

TitleLot Number
490070

References

Reference overview
Hah, J.M., et al. 2001. J. Med. Chem. 44, 2667.

Brochure

Title
Pathways and Biomarkers of Oxidative Stress
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-July-2010 JSW
Synonyms(4S)-N-(4-Amino-5[aminoethyl]aminopentyl)-Nʹ-nitroguanidine, TFA
DescriptionA cell-permeable, potent, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS) (Ki = 120 nM). Displays >2,500-fold and 192-fold selectivity over eNOS and iNOS, respectively.
FormWhite to off-white solid
FormulationSupplied as a dihydrate.
Intert gas (Yes/No) Packaged under inert gas
CAS number357965-99-2
Chemical formulaC₈H₂₁N₇O₂ · 3TFA · 2H₂O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHah, J.M., et al. 2001. J. Med. Chem. 44, 2667.