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500299 Nicotinamide

EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,FCC

Nicotinamide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Nicotinamide, Niacinamide, 3-Pyridinecarboxamide

CAS #: 98-92-0 EC Number: 202-713-4 Molar Mass: 122.13 g/mol Hill Formula: C₆H₆N₂O Grade: Ph Eur,BP,USP,JP,FCC
500299
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
98-92-0202-713-4C₆H₆N₂O122.13 g/molPh Eur,BP,USP,JP,FCC

Products

Catalogue NumberPackaging Qty/Pack
5.00299.9020 Fibre carton 20 kg
Description
Catalogue Number500299
SynonymsNicotinamide, Niacinamide, 3-Pyridinecarboxamide
References
Product Information
CAS number98-92-0
EC number202-713-4
GradePh Eur,BP,USP,JP,FCC
Hill FormulaC₆H₆N₂O
Molar Mass122.13 g/mol
HS Code2936 29 00
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point150 - 160 °C (0.0007 hPa)
Density1.40 g/cm3 (25 °C)
Flash point150 °C
Ignition temperature480 °C
Melting Point130 °C (sublimed)
pH value6.0 - 7.5 (50 g/l, H₂O, 20 °C)
Bulk density360 kg/m3
Solubility691 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 3530 - 3540 mg/kg
LD 50 dermalLD50 Rabbit > 2000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H319: Causes serious eye irritation.
Precautionary Statement(s)P264: Wash skin thoroughly after handling.
P280: Wear eye protection/ face protection.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337 + P313: If eye irritation persists: Get medical advice/ attention.
Signal WordWarning
RTECSQS3675000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerirritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
Assay (HPLC, calc. on dried substance)98.5 - 101.0 %
Identity (IR-spectrum) (Ph Eur)passes test
Identity (IR-spectrum) (USP)passes test
Identity (coloring 1)passes test
Identity (coloring 2)passes test
Identity (UV/VIS-Spectrum)passes test
AppearanceWhite to almost white, crystalline powder
Appearance of solution (50 g/l; water)Clear, colourless, not more intense in color than reference solution BY₇
pH (50 g/l; water)6.0 - 7.5
Melting range (lower value)≥ 128 °C
Melting range (upper value)≤ 131 °C
Absorption ratio (A 245 nm/A 262 nm)0.63 - 0.67
Chloride (Cl)≤ 210 ppm
Sulfate (SO₄)≤ 190 ppm
Pb (Lead)≤ 2 ppm
Residual solvents (ICH Q3C)excluded by production process
Readily carbonisable substancepasses test
Related substances (HPLC) (Major unspecified impurity)≤ 0.10 %
Related substances (HPLC) (Sum of all impurities)≤ 0.2 %
Sulfated ash (600 °C)
≤ 0.1 %
Loss on drying (Vacuum; 18 h)
≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP, FCC, JP.
Sulfated ash (600 °C)
≤ 0.1 %
Loss on drying (Vacuum; 18 h)
≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP, FCC, JP.
Global Trade Item Number
Catalogue Number GTIN
5.00299.9020 04022536722382

Documentation

Material Qualification Dossier

TitleVersion
5.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Nicotinamide SDS

Title

Safety Data Sheet (SDS) 

Nicotinamide Certificates of Analysis

Product Number PackagingSpecificationLot Number
5.00299.9020 Fibre cartonPDF Specification Document

Certificates

Title